Effects of triglyceride monohydroperoxides on the growth of E. coli.

Many experiments (1-4) have been done on the effect of autoxidized products of lipids on living animals, cells, enzymes and biological active substances. How ever, crude materials such as autoxidized TG or LA have, been used without further purification in most such experiments. In a previous paper (5), we report ed the effect of pure LAHPO on the growth of E. coll. LA can be used as a model substance for TG in studies concerns with the oxidation mechanism. Considerable difference can not be expected between TG and LA oxidation mechanism. How ever, there are some differences in their molecular structures and sizes. Recently, we prepared TG hydroperoxides (6, 7) from oxidized safflower oil and chrac terized their properties. In the present investigation we have attempted to examine the toxic effect of TG hydroperoxides on the growth of E. coli.